P90
نویسندگان
چکیده
منابع مشابه
The p90 RSK family members: common functions and isoform specificity.
The p90 ribosomal S6 kinases (RSK) are implicated in various cellular processes, including cell proliferation, survival, migration, and invasion. In cancer, RSKs modulate cell transformation, tumorigenesis, and metastasis. Indeed, changes in the expression of RSK isoforms have been reported in several malignancies, including breast, prostate, and lung cancers. Four RSK isoforms have been identi...
متن کاملActivation of p90 Is Sufficient for Differentiation of PC12 Cells
We investigated the role of Rsk proteins in the nerve growth factor (NGF) signaling pathway in PC12 cells. When rat Rsk1 or murine Rsk2 proteins were transiently expressed, NGF treatment (100 ng/ml for 3 days) caused threeand fivefold increases in Rsk1 and Rsk2 activities, respectively. Increased activation of both wild-type Rsk proteins could be achieved by coexpression of a constitutively act...
متن کاملp90: methamphetamine and traffic accidents
methamphetamine hydrochloride is a white to light brown crystalline powder, or clear chunky crystals resembling ice. the majority of street methamphetamine is produced in clandestine laboratories. the drug manufacturer states that patients should be informed that methamphetamine and amphetamine may impair the ability to engage in potentially hazardous activities such as driving a motor vehicle....
متن کاملFunctional interaction between p90 and Emi1 contributes to the metaphase arrest of mouse oocytes
Vertebrate eggs arrest at metaphase of the second meiotic division before fertilization under the effect of a cytostatic factor (CSF). This arrest is established during oocyte maturation by the MAPK kinase module, comprised of Mos, MEK, MAPKs and p90. Maintenance of CSF arrest at metaphase requires inhibitors of the anaphase-promoting complex (APC) like Emi1, which sequesters the APC activator ...
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ژورنال
عنوان ژورنال: European Journal of Cancer Supplements
سال: 2015
ISSN: 1359-6349
DOI: 10.1016/j.ejcsup.2015.08.077